Oncology
Oncology
We are dedicated to transforming cutting-edge scientific research into effective therapies that bring new hope to patients living with cancer.
Innovation Drug Pipeline
Projects
Target
Indications
PCC
IND
Phase I/II
Phase III
NDA
Launched
Projects：
DN022150
Target：
KRAS G12D
Indications：
Solid tumor
Projects
Target
Indications
PCC
IND
Phase I/II
Phase III
NDA
Launched
Marketed Products
Xinyang® Abiraterone Acetate Tablets
Xinyang® Abiraterone Acetate Tablets are a highly selective CYP17 enzyme inhibitor that targets multiple sites of androgen biosynthesis throughout the body.
Ligesitai® Sorafenib Tosylate Tablets
Ligesitai® Sorafenib Tosylate Tablets are a multi-target oral medication for treating tumors, with dual mechanisms of action. It inhibits tumor angiogenesis by blocking VEGFR and PDGFR and suppresses tumor cell proliferation by blocking the Raf/MEK/ERK signaling pathway, indirectly inhibiting tumor cell growth. It was approved for market in August 2020. It is primarily used for the treatment of renal cancer, liver cancer, and thyroid cancer.
Xinzhuo® Afatinib Dimaleate Tablets
Xinzhuo® Afatinib Dimaleate Tablets are the first irreversible ErbB family receptor blockers. They covalently bind to the kinase regions of EGFR (ErbB1), HER2 (ErbB2), and HER4 (ErbB4), irreversibly inhibiting tyrosine kinase autophosphorylation, leading to downregulation of ErbB signaling and inhibiting tumor cell proliferation. Xinchuo® was approved for market in August 2021 and is indicated for: Locally advanced or metastatic non-small cell lung cancer (NSCLC) with EGFR gene-sensitive mutations in patients who have not previously received EGFR tyrosine kinase inhibitors (TKI) treatment. Locally advanced or metastatic squamous cell carcinoma of non-small cell lung cancer (NSCLC) with disease progression during or after platinum-based chemotherapy.
